Congratulations, BioAge! (NASDAQ: BIOA)

Congratulations to Kristen Fortney, Eric Morgen, and the entire BioAge team on this week’s IPO!

BioAge is now a clinical-stage drug company developing therapeutic product candidates for metabolic diseases, such as obesity, by targeting the biology of human aging. The company’s differentiated discovery platform includes access to unique human datasets and has enabled it to uncover promising targets associated with aging and metabolic disease. 

BioAge’s lead product candidate is an orally-available, small molecule drug that offers the potential to drive improvements in weight loss and body composition in obese patients when combined with GLP-1 drugs. BioAge has also applied its platform to develop treatments for diseases driven by neuroinflammation.

Pear has a long history with BioAge and its co-founders, Kristen Fortney (CEO) and Eric Morgen (COO). I first met Kristen in 2015 when she was a postdoc at Stanford in Professor Stuart Kim’s lab, where she studied the genetics of extreme human longevity.  That year, Pear invested in BioAge’s initial seed financing, and we have gone on to successively back BioAge at every subsequent round, including the most recent Series D round

We’re incredibly proud of the team for making their public market debut today. The financing will help BioAge advance the clinical development of its existing pipeline, with the assessment of its lead product candidate in obesity in two separate Phase 2 studies – the first of which already kicked off this past July. 

This is also a moment to celebrate Kristen as a trailblazing CEO. Building a company is extremely difficult and Kristen’s leadership through ups and downs is commendable. Kristen had a clear vision from day one, surrounded herself by an incredible team from the beginning, and persevered against challenges.

I am delighted to have Kristen be our first female led IPO at Pear. In the tech industry, there still aren’t enough women running companies, and this is a real opportunity to celebrate that more women are rising through the ranks. In the 200+ year history of the NASDAQ, only 41 companies have been founded and led by women. We’re so pleased that this week, that number became 42. Congratulations, Kristen!

Introducing the Pear Emerging Managers in Residence 

We are excited to announce the Pear Emerging Manager in Residence, the first of its kind in the industry.

Early stage investing is more akin to company building than a finance job. You have to find amazing founders, building a great product, in a massive market, who can build a strong business that people love.

To find those people, it helps to have people who have been in the trenches before as operators. At Pear, our investment team have all been founders & operators. This helps us partner with top founders and help them go from zero to one.

At the same time, emerging managers are such an important and impactful part of the startup ecosystem. They have unique networks and access to dealflow as well as the hard earned scars on their backs from operating at early and growth stages. They can help founders accelerate their path to product market fit and beyond by sharing their deep knowledge from years of experience operating and building companies. 

Prior to joining Pear, I was part of this emerging manager ecosystem as a founder and managing partner at MKT1 Capital. I’ve seen first hand the impact emerging managers can have on a startup’s trajectory by helping in very specific ways. At MKT1 Capital, we helped founders hire their first marketer and build their marketing strategy. Most founders don’t come from a marketing background and most investors don’t, so it filled a clear gap in the ecosystem.

Part of what drew me to Pear is our intense focus on providing resources to founders in the areas they most need. We have an amazing talent team with decades of recruiting experience that helps founders make their first few hires. We have a GTM team who helps founders figure out how to bring their products to market with founder led sales.

Before joining Pear a few months ago, I started talking to Pejman and Mar about how we can help bring together the top operators turned emerging managers in a unique way. Today, I’m excited to introduce the Pear Emerging Manager in Residence Program, our newest program to help enrich the early stage ecosystem. We have four impressive operators turned emerging managers who will work closely with us at Pear to help them build their funds while also partnering on investments to help founders that need their unique superpowers. They will have access to Pear Studio and Pear will invest directly in their funds. 

I’m proud to introduce our inaugural Pear Emerging Managers in Residence:

Sarah Smith, The Sarah Smith Fund, a $25M pre-seed & seed fund 

Sarah has been both an operator and investor. She held leadership roles at Facebook and Quora during massive growth inflection points before joining Bain Ventures as a Partner. When a founder is involved in a company over the long haul, the company is 4-5x more likely to be a top 25% performing equity in the public markets. Sarah’s fund is focused on identifying outlier founders and supporting them with people operations expertise. We have seen first hand the impact she makes in working closely with top founders as they build their companies, so much so that founders seek out her unique approach and want her on their cap table. 

John Gleeson, Success Venture Partners, a $10M pre-seed & seed fund

Prior to starting Success Venture Partners, John served as VP of Customer Success at Motive where he played a pivotal role in helping the company grow from $1M to over $300M in revenue. He also co-hosts the largest Customer Success Meetup in the world, with quarterly events in San Francisco and New York City. Founders seek John’s expertise in building founder-led Customer Success at the earliest stages to ensure early customers renew, locking in product market fit, building the GTM machines and setting the company on a path to world-class Net Dollar Retention. SuccessVP includes over 75 LPs, many of whom are Chief Customer Officers from companies like Toast, Slack, GitHub, Braze, Monday.com, and Notion. 

David Ongchoco, Comma Capital, a $10M pre-seed fund

David started his career by writing about startup founders and investors for the Huffington Post and Inc. Magazine. He was spent time operating at companies like Uber, Amplitude, Rutter, and more. He spent time learning bout venture capital at Dorm Room Fund and through fellowships at Learn Capital and True Ventures. At Comma Capital, he has built the strongest community of Gen-Z and Millennial engineers and startup founders. They support early to mid career engineers and builders through their Comma Collective community, in=person event series in NYC and SF and programs focused on the first 3-6 months of starting a company. 

Adarsh Bhatt, Comma Capital, a $10M pre-seed fund

Adarsh started his career in the hedge fund and growth equity world in places like Moon Capital and HQ Capital before making his way to operating roles at Truepill, Flexpa, and Dukkantek. He co-founded Comma Capital with David to support early to mid career engineers and builders at the earliest stages of their journey. 

We look forward to continuing to find ways to partner with top emerging managers who specifically come from operating backgrounds to help build the next generation of iconic companies. 

Fall Speaker Series

Pear VC is pleased to be hosting a Fall speakers series in Pear Studio Menlo Park and Pear Studio San Francisco. We have invited prominent tech leaders to join us for conversations on effective leadership, entrepreneurship, and lessons learned throughout their careers. This Fall, we’ll host conversations with these tech leaders:

  • Dara Khosrowshahi – CEO of Uber
  • Vladimir Tenev – Co-founder and CEO of Robinhood
  • Adam Foroughi – Co-founder and CEO of AppLovin
  • Pedro Franceschi – Founder and CEO of Brex
  • Tony Xu – Co-founder and CEO of DoorDash
  • Vinod Khosla – Founder of Khosla Ventures

We’re looking forward to an exciting Fall!

Orby AI closes $30M Series A to continue building AI Agents for the Enterprise

Orby AI recently announced its $30 million Series A round, co-led by NEA, Wing Venture Capital, and WndrCo, with participation from Pear VC. We are proud to be Orby’s earliest investors (when a LinkedIn message from their CEO first connected us) and we are thrilled to continue our support now.

Orby’s Enterprise AI Automation tool automates complex workflows by observing users at work, identifying repetitive tasks, and writing the code to automate those tasks. Within minutes, a custom automation is ready to be implemented with user approval. 

This is game changing.

Orby AI is Changing the Game by Disrupting Process Automation Market

Co-founder and CEO Bella Liu was heading AI Product at UI Path, a leading business automation software company, when she was first inspired with the idea behind Orby. At the time, the RPA (robotics process automation) software being used relied on human users to input specific “if this, then that” rules, which turned out to be rather fragile. For example, a user who frequently opens invoices and transfers numbers to a spreadsheet must specify exactly which buttons to click and where on the screen those buttons will be— a system that is prone to error, slow, and hard to scale. 

Orby AI’s Model Learns and Implements Without User Input

Orby’s approach to business automation is a huge leap forward. Unlike traditional RPA models, Orby’s LAM (Large Action Model) approach means their product doesn’t need to be told which tasks to automate, or how. Orby simply observes a user at work, learns what could be automated, and creates the actions to implement it. The user just approves the process and can correct the model at any time, thus continuously helping Orby improve.

Why We Chose Orby AI

We’re very excited about Orby’s team. Co-founders Bella Liu and Will Lu bring deep experience and expertise in the AI and automation technology space. Bella (CEO) was previously the AI product leader at UiPath, from early-stage to post-IPO. Will (CTO) was previously the data platform leader at Google Cloud AI and was involved in three AI products with real world deployments within Google. Orby’s team was a great founder-market match for Pear’s thesis on AI automation for human to machine and machine to machine automation. We are pleased to have backed Orby early on, and remain certain they are the right group to work on this problem.

What Orby AI Does

Before partnering with Orby, the Pear team was already deeply interested in AI automation for enterprise applications, aiming to solve specific problems within distinct industries one vertical at a time. They believed that the kinds of AI tools which could understand specific use cases, gather necessary datasets, and execute targeted solutions were the future. Additionally, they had a thesis that semantic understanding of workflows, enabled by backend interaction data, could enhance the generalizability of RPA.

Orby’s team embraced a similar approach but expanded it to build a horizontal enterprise AI automation platform applicable across many verticals. Initially focusing on widely used workflows like invoice processing and expense auditing, they aimed to enhance their action-based foundational models. This led to the creation of a platform that delivers immediate value in various enterprise scenarios while achieving general-purpose AI automation.

Orby is pioneering a Generative Process Automation (GPA) platform, leveraging the industry’s first Large Action Model (LAM) for enterprise use. This platform enhances efficiency by enabling teams to automate complex tasks independently. Orby’s multimodal large action model, combined with an AI agent capable of symbolic reasoning and neural network analysis, seamlessly handles intricate automation requests.

When tasked with an assignment, Orby’s AI autonomously generates workflows, integrating with specialized AI agents for sub-tasks such as data analysis or customer interaction. By learning and automating workflows contextually and semantically, Orby surpasses traditional RPA systems. The LAMs empower Orby’s AI to understand and automate repetitive processes across unstructured datasets, emulating human capabilities.

This neuro-symbolic programming captures standard process flows and ensures robust exception handling, making AI-driven automation accessible and efficient for enterprises. Orby’s patented technology, which combines LAMs with advanced programming techniques, empowers workers to automate tasks without needing technical assistance. The system continuously learns and adapts, improving productivity and efficiency over time.

Market Opportunity

The market potential for automation in enterprises has been evidenced by the success of Robotic Process Automation (RPA). However, AI Process Automation, like that offered by Orby, goes beyond traditional RPA by making previously uneconomical use cases viable. The return on investment (ROI) for RPA is often hindered by high implementation and maintenance costs, limiting its applicability.

Orby’s innovative approach addresses two critical challenges of RPA:

1. Semantic understanding of automatable workflows versus fragile rule-based systems.

2. Hands-off, continuous online learning and improvement of both workflow discovery and implementation.

By discovering automatable repetitive workflows and generating maintenance-free AI automations, Orby significantly reduces implementation and maintenance costs. This makes a much larger share of repeatable workflows candidates for automation, substantially improving ROI and expanding an already large market.

This advancement is not merely an efficiency gain for high-volume, repeatable workflows. Imagine an AI capable of automating any workflow, regardless of volume, simply by demonstrating the process. This capability would enable enterprises to innovate their workflows at an accelerated pace, shifting focus to strategic improvements. In this competitive landscape, no enterprise can afford to ignore such technology, as those who adopt it will innovate faster.

To provide a baseline, a 2017 McKinsey Future of Work report estimates that 60% of jobs involve at least 30% repetitive tasks that can be automated. Orby has already demonstrated massive productivity gains in several Fortune 500 companies through successful use cases. This is just the beginning; the market opportunity is far greater.

How we partnered together

After funding Orby’s seed round in July 2022, in addition to our close partnership on product and vision, we leveraged the full Pear team to partner with them in the following two years. Ana Leyva and Pepe Agell worked with the Orby team on their product-market fit and GTM strategy, and Jill Puente helped them in marketing and PR, including landing the Business Insider piece announcing the initial seed round. Nate Hirsch from Pear’s talent team helped Orby hire eight out of their first ten team members (eight engineers, two designers, and a recruiter). When it was time for Orby’s Series A raise, the company went through Pear’s fundraising bootcamp with Mar’s full support behind them. As we say to founders at Pear: if you get one of us, you get all of us as partners.

We’re excited to have been supporting Orby AI since day one and look forward to their promising journey ahead!

Arash and Bella at our AGM summit in March 2024.

PearX S21 alum Valar Labs raises $22M to continue building AI that helps oncologists make better decisions

Last week, PearX S21 alum, Valar Labs, announced its $22 million Series A round co-led by DCVC and a16z with participation from Pear. We’re incredibly excited for this milestone for Valar Labs and wanted to take this opportunity to look back on our history working with their team.

We met the Valar Labs co-founders at a free boba event we hosted on Stanford’s campus in 2020. After that first meeting and introduction, the Valar Labs team applied to Pear Competition. And from there, they joined our PearX S21 cohort. 

PearX S21 cohort, which included companies including: Valar Labs, Kale, and Aklivity

When we met the team, we were incredibly excited to back them for a few big reasons:

  • This is a massive and unsolved market opportunity. Valar is using AI to help oncologists choose the correct treatment for their patients. Unfortunately, for thousands of cancer patients each year, there is a high degree of uncertainty around which treatment option works best for them. This uncertainty leads to billions of dollars of potentially unnecessary drug costs, and even more importantly, wastes precious time for thousands of patients battling cancer. The sad reality is that most cancer patients end up on a treatment sequence that fails them, and Valar Labs is on a mission to change that.
  • The team had a clear vision for the type of product that could best meet this unmet need. Valar is truly a software company that enables capabilities that legacy diagnostic companies do not have. Unlike many diagnostics companies for which the core technology revolves around a novel laboratory assay, Valar uses AI to analyze images of a patient’s tumor and to predict the likelihood of response to different standard-of-care treatments. This information helps oncologists determine the best treatment pathway for a patient.
  • The team was well suited to tackle this problem: Valar’s co-founders, Anirudh JoshiViswesh Krishna, and Damir Vrabac, met at Stanford in 2020 when they were all part of Dr. Andrew Ng’s machine learning group. While at Stanford, they had the opportunity to spend time at the intersection of AI and medicine, speak to hundreds of oncologists, and find the key areas of high medical unmet need. Not only were they had were innately curious and incredibly quick learners, they also gathered the most esteemed KOLs in the space including Professor Eric Collison from UCSF and Professor Pranav Rajpurkar from Harvard/Stanford  to solve this problem. 

The team hit the ground running during PearX, and the Pear team was there to assist them in hiring their first employee, introduce them to strategic advisors on both go-to-market and the clinical side, and get their story in shape for fundraising. While whiteboarding with the team, it was clear that to be successful, they needed data access and partnerships with cancer centers. 

Valar’s Demo Day pitch in October 2021

Upon completing PearX, Valar hit a number of milestones in their company growth. After Demo Day, Valar Labs closed their seed round of $4.15M led by the a16z Bio + Health fund. They’ve leveraged their seed funding to reach clinical validation and form partnerships with top academic and medical institutions, and they’ve unveiled Vesta, the first-ever, AI-based oncology test for bladder cancer.  

Anirudh and the Pear team

When we first met Valar Labs, they were 3 founders operating out of a dorm room. Now they are more than 14 employees with $26M raised. Their growth path has been incredible to date and we know the best is yet to come for this team. 

Pear + Open AI Hackathon

Pear and OpenAI teamed up to welcome over 150 hackers to Pear Studio SF for our first ever hackathon on April 27th! Kicking off bright and early at 9:00 am, the space was buzzing with energy as hackers dove into their projects, brainstorming and coming up with some seriously cool ideas. We had 49 teams submit projects and were completely blown away by the quality of execution and the diversity of ideas.

Winners:

Congratulations to all of the finalists and category prize winners! 🏆 

Winners:

Finalists:

Here is the full gallery of projects built at the hackathon. There’s an incredible variety of ideas and innovations created in a single day.

Founders Panel:

Aparna Sinha (Advisor, former Pear AI/ML Partner) also hosted a founder panel with Harrison Chase (Co-Founder/CEO at Langchain), Shreya Rajpal (Co-Founder/CEO at Guardrails AI), Rayan Krishnan (Co-Founder/CEO at vals.ai), and Simon Suo (Co-Founder/CTO at LlamaIndex). We discussed what type of problem each of their companies solves, addressing Data, RAG, reliability, and Eval, and what future areas are most important, such as multimodality, new model architectures, and agents.

About PearX:

PearX invests between $250k to $2mn, and offers access to Pear Studio SF, bespoke recruiting support to close your first hires, GTM support to acquire your first customers, and a dedicated Pear partner who works directly with you. PearX alumni have raised over $2bn in follow-on capital.

Some more pictures from the day:

This hackathon not only highlighted the immense talent within the AI community but also reinforced the potential of AI-driven capabilities in addressing real-world problems. We can’t wait to host another hackathon again soon, and we hope to see you there!

Celebrating 100 hires for Pear companies 🥳

Last February, we introduced Pear Talent Services to the public. At the core of our announcement was our promise to directly hire the most crucial talent for our founders—a commitment we extend to every company we invest in. Today, we’re thrilled to announce that we’ve made 100 hires for our founders, marking a significant milestone in our journey.

To mark this occasion, we wanted to share a few trends that emerged from our initial 100 hires.

We specialize in supporting early stage companies and the distribution of hires reflects just that.

The vast majority of hires made were technical, particularly founding or early Engineers.

75% of hires came directly from other tech companies. 

21% of hires attended either Stanford, CMU or Berkeley.

Hiring has shifted back to in-person or hybrid roles, with only 25% of positions being remote.

If you’re a founder interested in learning more about our Talent Service offering, click here.

Welcoming Ana Leyva to the team!

Pear is thrilled to welcome Ana Leyva to our go-to-market team! Ana’s journey is a testament to her passion for the startup ecosystem, with past roles at tech unicorns Box, ServiceTitan, and Vanta. We’re so excited to have her onboard as part of our GTM team, offering her first-hand experience as a seasoned operator. 

In her short time with us, Ana has already supported over 30 Pear companies, strategizing with them on all things GTM. This includes many critical steps of sales like: nailing ICP, prospecting, customer discovery, messaging, and more. 

A Bay Area native, Ana is a first-generation college graduate from Princeton University and holds an MBA/MA in Education from Stanford. After graduating from Princeton, she joined Box pre-IPO at Series E. At Box, she was hooked on startup culture, especially the GTM and commercial arms. Following Box, she was an early sales hire at ServiceTitan and then, while at Stanford GSB, worked with Vanta to hone their early sales motion. Following business school, Ana became a founder and CEO herself with her ed-tech startup Lelu. Ana embodies the entrepreneurial spirit that Pear champions. 

“From early on, I saw both Mar and Pejman champion founders in a way that was genuine and authentic. That authenticity and commitment to being helpful is the backbone of Pear’s culture and makes it stand out in the sea of VCs.”

Ana was a Pear Fellow while at Stanford GSB, and we’re so excited to have her with us full time. She hosts Winning Wednesdays, a bi-weekly webinar series on GTM topics, and will continue to build out Pear’s GTM programming. 
Interested in connecting with Ana? Email her at ana@pear.vc.

Welcoming Hannah Berke to Pear!

We’re excited to announce that Hannah Berke joined Pear a few months ago as part of our Community + Operations team! A seasoned community leader, we can’t wait to have her on board, especially after our recent Pear Studio SF expansion. 

Born and raised in Chattanooga, Tennessee, Hannah was introduced to the Bay Area as an undergraduate at Stanford. As an undergrad, Hannah worked in technology integration and strategic communications at Amazon and MongoDB. She was also deeply involved in university life, serving in a number of different university offices, including the Board of Trustees, and community groups. “I learned the impact that a strong community can have on someone’s success— and that I was super passionate about creating those types of environments for people.” 

Hannah first encountered Pear through a classmate and friend who participated in PearX. She’d been hooked on startup culture ever since arriving at Stanford, and Pear’s founder-first approach stood out among VCs— “the mentality of giving before getting”. At Pear, Hannah now supports this goal, creating the community support founders need to build the best companies possible. 

“Mar and Pejman’s vision for a best-in-class ecosystem and community of tech builders is amazing, and I’m honored I get to be a part of bringing it to life.”

We’re thrilled to have Hannah on board. You can reach her at hannah@pear.vc.

PearX: join the ranks of elite founders

The most elite founders walk through walls to build category-defining companies. They are unique individuals, who don’t come by very often. Having seeded and helped build companies like DoorDash, Dropbox, Vanta, Aurora Solar, Gusto, Guardant Health and Affinity from their earliest days, we know what these founders look like and what they need. We have developed PearX to partner and support the very best entrepreneurs at the very beginning of their journey to help them get to the next stage. 

We believe small cohorts of less than 20 teams give PearX companies a disproportionate advantage. As a result, 90% of our PearX alums go on to secure funding following our Demo Day. Pear’s unparalleled resources lead to these unrivaled results. Here are some of the things we offer to each PearX company.

  • Capital to build your company, your way: We invest between $250k and $2M in all PearX companies. We know that some founders only need a small amount of capital to ideate and other teams are in more cost-intensive verticals that require more funding. All companies are unique so we’ll work with you. 
  • Founder to founder: Work 1:1 with a partner who has been in your shoes and knows your industry. Our team has started and sold 10 companies to the likes of Cisco, Instacart, Plaid, and Zynga.
  • Join the best community: Entrepreneurship doesn’t have to be a lonely journey. Joining PearX means joining a community of like-minded founders. We kick off each cohort with Camp Pear: a 3-day retreat for the entire cohort to come together, learn key company building tactics, and get to know one another. Not only will you work alongside your PearX batch for 14+ weeks, but you’ll also have the wider PearX alumni network to lean on. 
  • Access Pear Studio: Everyone in PearX receives dedicated office space in Pear Studio SF, our 30,000 square foot state-of-the-art office space with standing desks, conference rooms, phone booths, and more. This space is completely free to you for the first 12 months.
  • Build a scalable sales motion: Our go-to-market team, Pepe and Ana, will guide you through the critical steps of sales: nailing ICP, prospecting, customer discovery, messaging, and more. 
  • Recruit the best talent: Our dedicated PearX Recruiter, Nate, will find your founding engineer, co-founder, or whatever critical hire your team needs. In the last two cohorts, Nate has hired 25 people for our PearX companies. Nate leads the full cycle of recruiting for your team – from sourcing to closing candidates. This is an unprecedented level of support for an accelerator, but that’s how much we believe that hiring impacts company building. Last batch, Nate hired an average of two people per PearX company.
  • Fundraise strategically: We help you raise additional capital when you’re ready. From perfecting the story and creating a pitch deck to creating a target investor list and negotiating and closing your round. In fact, 90% of companies that go through PearX raise capital from institutional investors.

Are you interested in joining our PearX S24 cohort? We’re actively looking for our next batch of founders, and we’d love to hear from you. Please apply at pear.vc/pearx!